浙江大学药学院生物技术药物制剂研究室
有意向者可通过以下方式联系：
浙江大学药学院生物技术药物制剂研究室 高建青教授
浙江省杭州市西湖区余杭塘路866号浙江大学紫金港校区药学院409室邮编310058
联系人邮箱：gaojianqing@zju.edu.cn电话：0571-88208437
研究室主页http://10.71.128.1/D.BTP/Main%20index.htm
一、招聘条件及要求：
1.具备药剂学、生物材料/高分子材料学、分子生物学、免疫学、细胞生物学等相关专业博士学位；
2.有较强的与人沟通能力及团队合作精神，英语能力突出，诚实敬业，有责任心。
二、招聘研究方向：
1.干细胞在DDS中的应用
2．靶向制剂及其靶向机制研究
3. 纳米制剂克服耐药研究
三、工作和生活待遇：
除享受浙
四、应聘者需提供的材料：
1.简历（自大学开始至今不间断的学习、工作简历，包括充分反映本人学术水平的材料，列出著作、论文、科研项目、获奖成果等）。
2.提供两名推荐或经历证明人的联系方式。
课题组在研代表性项目：
国家自然科学基金，高效载体共导入肿瘤抗原和趋化性细胞因子受体提高树突状细胞体内定位及抗原提呈能力的研究
国家自然科学基金，基于干细胞的新型靶向复合生物基因载体的构建与其对缺血性脑卒中的治疗研究
国家自然科学基金，MSCs作为新型活性生物基因靶向载体的可行性及其机制考察
国家自然科学基金，基于干细胞基因修饰治疗神经损伤的PPFLMLKGSTR肽-透明质酸凝胶的构建及多尺度力学研究
国家自然科学基金，基于重组表皮干细胞与三维纳米纤维支架的仿生制剂的构建与体内外评价
浙江省自然科学基金，双配体修饰的脂质体脑胶质瘤二级靶向给药系统的研究
课题组近年代表性论文：
1. Min Han, Qing Lv, Xin-Jiang Tang, Yu-Lan Hu, Dong-Hang Xu, Fan-Zhu Li, Wen-Quan Liang, Jian-Qing Gao*, Overcoming drug resistance of MCF-7/ADR cells by altering intracellular distribution of doxorubicin via MVP knockdown with a novel siRNA polyamidoamine-hyaluronic acid complex, J Control Release, 2012, 163:136-144(Cover Story)
2. Yu-Lan Hu, Bing Huang, Tian-Yuan Zhang, Pei-Hong Miao, Yasuhiko Tabata, Jian-Qing Gao*, Mesenchymal stem cells as a novel carrier for targeted-delivery of gene in cancer therapy based on non-viral transfection, Mol Pharm, 2012,9:2698-2709
3. Bing Huang, Yasuhiko Tabata, Jian-Qing Gao*, Mesenchymal stem cells as therapeutic agents and potential targeted gene delivery vehicle for brain diseases, J Control Release, 2012,162:464-473
4. Xing-Lei Yao, Yasuo Yoshioka, Yu-Zhe Chen, Gui-Xing Ruan, Hiroyuki Mizuguchi, Yohe Mukai, Naoki Okada, Jian-Qing Gao*, Shinsaku Nakagawa*,Construction of PEGylated adenovirus vector with targeting peptides for cancer gene therapy, Biomacromolecules, 2012 Aug 13;13(8):2402-9
5. Li-Hua Peng, Suk-Ying Tsang, Yasuhiko Tabata, Jian-Qing Gao*, Genetically-manipulated adult stem cells as therapeutic agents and gene delivery vehicle for wound repair and regeneration, J Control Release., 2012.157：321-333
6. Li-Hua Peng, Kwok-Pui Fung, Ping-Chung Leung, Jian-Qing Gao*, Stem cell based gene delivery system for wound therapy, Drug Discovery Today, 2011,16(21/22):957-966
7. Ni Li, Li-Hua Peng, Xi Chen, Shinsaku Nakagawa, Jian-Qing Gao*, Transcutaneous vaccines: novel advances in technology and delivery for overcoming the barriers, Vaccine, 2011 Aug 26;29(37):6179-90.
8. Cai-Xia He, Ni Li, Yu-Lan Hu, Xiu-Mei Zhu, Hai-Jie Li, Min Han, Pei-Hong Miao, Zhong-Jie Hu, Gang Wang, Wen-Quan Liang, Yasuhiko Tabata, Jian-Qing Gao*, Effective gene delivery to mesenchymal stem cells based on the novel reverse transfection and three-dimensional cell culture system, Pharm Res, 2011, 28(7):1577-1590
9. Chen J, Yu Z, Chen H, Gao J, Liang W, Transfection efficiency and intracellular fate of polycation liposomes combined with protamine. Biomaterials. 2011 Feb;32(5):1412-8
10. Yu-Lan Hu, Ying-Hua Fu, Yasuhiko Tabata, Jian-Qing Gao*, Mesenchymal stem cells: a promising targeted-delivery vehicle in cancer gene therapy, J Control Release, 2010,147：154-162
11. Cai-Xia He, Yasuhiko Tabata, Jian-Qing Gao*, Non-viral gene delivery carrier and its three dimensional transfection system. Int J Pharm, 2010;386:232-242
12. Min Han, Cai-Xia He, Qiu-Li Fang, Xiao-Chun Yang, Yuan-Yuan Diao, Dong-Hang Xu, Qiao-Jun He, Yong-Zhou Hu, Wen-Quan Liang, Bo Yang, Jian-Qing Gao*, A novel camptothecin derivative incorporated in nano-carrier induced distinguished improvement in solubility, stability and anti-tumor activity both in vitro and in vivo, Pharm. Res, 2009 Apr;26(4):926-35
友情链接